Reactome | LDL translocates from endosome lumen to lysosome lumen

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LDL translocates from endosome lumen to lysosome lumen Show undefined attributes

category	omitted
compartment	[Compartment:171907] endosome lumen [Compartment:161320] lysosomal lumen
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10424120
displayName	LDL translocates from endosome lumen to lysosome lumen
eventOf	[Pathway:R-BTA-8964038] LDL clearance - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-8865667] LIPA hydrolyses sterol esters to sterols and fatty acids - Bos taurus
inferredFrom	[BlackBoxEvent:R-HSA-8876366] LDL translocates from endosome lumen to lysosome lumen - Homo sapiens
input	[Complex:R-BTA-171082] LDL [endosome lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	LDL translocates from endosome lumen to lysosome lumen
output	[Complex:R-BTA-8876367] LDL [lysosomal lumen]
precedingEvent	[Reaction:R-BTA-171106] LDLR:LDL complex => LDLR + LDL - Bos taurus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48898] Bos taurus
stId	R-BTA-8876366
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-8964038] LDL clearance
(precedingEvent)	[Reaction:R-BTA-8865667] LIPA hydrolyses sterol esters to sterols and fatty acids
(inferredTo)	[BlackBoxEvent:R-HSA-8876366] LDL translocates from endosome lumen to lysosome lumen

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