Reactome | HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10423940] guanyl-nucleotide exchange factor activity of HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10423937
displayName	HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane]
hasComponent	[Complex:R-BTA-8875548] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] [EntityWithAccessionedSequence:R-BTA-913472] RAPGEF1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8875561] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] - Homo sapiens
maxDepth	8
name	HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1
producedByEvent	[Reaction:R-BTA-8875558] RAPGEF1 binds CRK,CRKL - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-8875561
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10423940] guanyl-nucleotide exchange factor activity of HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane]
(output)	[Reaction:R-BTA-8875558] RAPGEF1 binds CRK,CRKL
(inferredTo)	[Complex:R-HSA-8875561] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane]

Cite Us!