Reactome | MBTPS2 (S2P) cleaves CREB3L3

Schema > Reaction > Entries

MBTPS2 (S2P) cleaves CREB3L3 Show undefined attributes

catalystActivity	[CatalystActivity:10362621] metalloendopeptidase activity of MBTPS2 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10423664
displayName	MBTPS2 (S2P) cleaves CREB3L3
eventOf	[Pathway:R-BTA-8874211] CREB3 factors activate genes - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-BTA-8874202] CREB3L3 translocates from the cytosol to the nucleus - Bos taurus
inferredFrom	[Reaction:R-HSA-8874201] MBTPS2 (S2P) cleaves CREB3L3 - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-8874158] CREB3L3 [Golgi membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	MBTPS2 (S2P) cleaves CREB3L3
output	[EntityWithAccessionedSequence:R-BTA-8874214] CREB3L3 [cytosol] [EntityWithAccessionedSequence:R-BTA-8874183] CREB3L3 [Golgi membrane]
precedingEvent	[Reaction:R-BTA-8874206] MBTPS1 (S1P) cleaves CREB3L3 - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-8874201
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-8874211] CREB3 factors activate genes
(precedingEvent)	[BlackBoxEvent:R-BTA-8874202] CREB3L3 translocates from the cytosol to the nucleus
(inferredTo)	[Reaction:R-HSA-8874201] MBTPS2 (S2P) cleaves CREB3L3

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