Reactome | PAFAH2 hydrolyses PAF to lyso-PAF and acetate

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PAFAH2 hydrolyses PAF to lyso-PAF and acetate Show undefined attributes

catalystActivity	[CatalystActivity:10422932] 1-alkyl-2-acetylglycerophosphocholine esterase activity of PAFAH2 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10422934
displayName	PAFAH2 hydrolyses PAF to lyso-PAF and acetate
eventOf	[Pathway:R-BTA-418346] Platelet homeostasis - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8869206] PAFAH2 hydrolyses PAF to lyso-PAF and acetate - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-8869214] PAF [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	PAFAH2 hydrolyses PAF to lyso-PAF and acetate
output	[SimpleEntity:R-ALL-29416] CH3COO- [cytosol] [SimpleEntity:R-ALL-8869207] lyso-PAF [endoplasmic reticulum membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-8869206
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-418346] Platelet homeostasis
(inferredTo)	[Reaction:R-HSA-8869206] PAFAH2 hydrolyses PAF to lyso-PAF and acetate

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