Reactome | Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors

Schema > Pathway > Entries

Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors Show undefined attributes

created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10444366
displayName	Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
eventOf	[Pathway:R-BTA-212436] Generic Transcription Pathway - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:81881] regulation of transcription by RNA polymerase II
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-BTA-8866907] Activation of the TFAP2 (AP-2) family of transcription factors - Bos taurus [Pathway:R-BTA-8866910] TFAP2 (AP-2) family regulates transcription of growth factors and their receptors - Bos taurus [Pathway:R-BTA-8866911] TFAP2 (AP-2) family regulates transcription of cell cycle factors - Bos taurus [Pathway:R-BTA-8869496] TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation - Bos taurus [Reaction:R-BTA-8869580] DEK binds TFAP2A homodimers - Bos taurus [Pathway:R-BTA-8866904] Negative regulation of activity of TFAP2 (AP-2) family transcription factors - Bos taurus
inferredFrom	[Pathway:R-HSA-8864260] Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-8864260
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-212436] Generic Transcription Pathway
(inferredTo)	[Pathway:R-HSA-8864260] Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors

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