Reactome | LYZ hydrolyzes peptidoglycans in the bacterial cell wall

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LYZ hydrolyzes peptidoglycans in the bacterial cell wall Show undefined attributes

catalystActivity	[CatalystActivity:10421801] lysozyme activity of LYZ:PGN [extracellular region]
category	omitted
compartment	[Compartment:984] extracellular region [Compartment:25409] peptidoglycan-based cell wall
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10421803
displayName	LYZ hydrolyzes peptidoglycans in the bacterial cell wall
eventOf	[Pathway:R-BTA-6803157] Antimicrobial peptides - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-8862320] LYZ hydrolyzes peptidoglycans in the bacterial cell wall - Homo sapiens
input	[SimpleEntity:R-ALL-109276] H2O [extracellular region] [Complex:R-BTA-8862293] LYZ:PGN [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	LYZ hydrolyzes peptidoglycans in the bacterial cell wall LYZ hydrolyzes beta 1->4 linkages of between GlcNAc and MurNAc
output	[SimpleEntity:R-ALL-6788982] betaGlcNAc [peptidoglycan-based cell wall] [Complex:R-ALL-6788991] MurNAc:Peptide [peptidoglycan-based cell wall]
precedingEvent	[Reaction:R-BTA-8862300] LYZ binds bacterial peptidoglycan - Bos taurus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48898] Bos taurus
stId	R-BTA-8862320
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-6803157] Antimicrobial peptides
(inferredTo)	[BlackBoxEvent:R-HSA-8862320] LYZ hydrolyzes peptidoglycans in the bacterial cell wall

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