Reactome | 2x RET:GFRA:GDNF complexes [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10420943] transmembrane receptor protein tyrosine kinase activity of 2x RET:GFRA:GDNF complexes [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-BTA-8854908] PKA phosphorylates RET:GDNF:GFRA dimer - Bos taurus [Reaction:R-BTA-8853792] RET tyrosine phosphorylation - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10420918
displayName	2x RET:GFRA:GDNF complexes [plasma membrane]
hasComponent	2 × [DefinedSet:R-BTA-8853817] RET:GFRA:GDNF complexes [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-8855760] 2x p-S696-RET:GFRA:GDNF complexes [plasma membrane] - Homo sapiens [Complex:R-HSA-8853818] 2x RET:GFRA:GDNF complexes [plasma membrane] - Homo sapiens
maxDepth	6
name	2x RET:GFRA:GDNF complexes
producedByEvent	[Reaction:R-BTA-8854908] PKA phosphorylates RET:GDNF:GFRA dimer - Bos taurus [Reaction:R-BTA-8853762] RET dimerizes - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-8853818
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-BTA-8854908] PKA phosphorylates RET:GDNF:GFRA dimer [Reaction:R-BTA-8853762] RET dimerizes
(input)	[Reaction:R-BTA-8854908] PKA phosphorylates RET:GDNF:GFRA dimer [Reaction:R-BTA-8853792] RET tyrosine phosphorylation
(inferredTo)	[Complex:R-HSA-8855760] 2x p-S696-RET:GFRA:GDNF complexes [plasma membrane] [Complex:R-HSA-8853818] 2x RET:GFRA:GDNF complexes [plasma membrane]
(physicalEntity)	[CatalystActivity:10420943] transmembrane receptor protein tyrosine kinase activity of 2x RET:GFRA:GDNF complexes [plasma membrane]