Reactome | Dehalogenation of carbon tetrachloride to form a free radical

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Dehalogenation of carbon tetrachloride to form a free radical Show undefined attributes

catalystActivity	[CatalystActivity:10338862] monooxygenase activity of Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:17960] smooth endoplasmic reticulum
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10338881
displayName	Dehalogenation of carbon tetrachloride to form a free radical
eventOf	[Pathway:R-BTA-211999] CYP2E1 reactions - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:10012] carbon tetrachloride metabolic process
inferredFrom	[Reaction:R-HSA-76434] Dehalogenation of carbon tetrachloride to form a free radical - Homo sapiens
input	[SimpleEntity:R-ALL-40887] CCl4 [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	Dehalogenation of carbon tetrachloride to form a free radical Dehalogenation of the haloalkane CCl4 to form CCl3. free radical
output	[SimpleEntity:R-ALL-29572] Cl- [endoplasmic reticulum lumen] [OtherEntity:R-ALL-76433] Trichloromethyl radical [endoplasmic reticulum lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-76434
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-211999] CYP2E1 reactions
(inferredTo)	[Reaction:R-HSA-76434] Dehalogenation of carbon tetrachloride to form a free radical

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