Reactome | glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated]

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glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] Show undefined attributes

catalystActivity	[CatalystActivity:10338625] glycerol-3-phosphate O-acyltransferase activity of GPAM or GPAT2 [mitochondrial outer membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10338627
displayName	glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated]
eventOf	[Pathway:R-BTA-75109] Triglyceride biosynthesis - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT) - Bos taurus
inferredFrom	[Reaction:R-HSA-75886] glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] - Homo sapiens
input	[SimpleEntity:R-ALL-75967] FACoA [cytosol] [SimpleEntity:R-ALL-76114] G3P [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] Conversion of glycerol-3-phosphate to lysophosphatidic acid
output	[SimpleEntity:R-ALL-76112] 1-acyl LPA [cytosol] [SimpleEntity:R-ALL-76194] CoA-SH [cytosol]
precedingEvent	[Reaction:R-BTA-75887] Conversion of Glycerol to Glycerol-3-phosphate - Bos taurus [Reaction:R-BTA-75889] DHAP is converted to G3P by GPD1/GPD1L - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-75886
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-75109] Triglyceride biosynthesis
(precedingEvent)	[Reaction:R-BTA-75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT)
(inferredTo)	[Reaction:R-HSA-75886] glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated]

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