Reactome | Abortive Initiation Before Second Transition

Schema > Reaction > Entries

Abortive Initiation Before Second Transition Show undefined attributes

category	dissociation
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10338511
displayName	Abortive Initiation Before Second Transition
eventOf	[Pathway:R-BTA-674695] RNA Polymerase II Pre-transcription Events - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-75856] Abortive Initiation Before Second Transition - Homo sapiens
input	[Complex:R-BTA-75859] Pol II Promoter Escape Complex [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Abortive Initiation Before Second Transition
output	[OtherEntity:R-ALL-110068] DNA containing Pol II promoter with transcript with 2 or 3 nucleotides [nucleoplasm] [EntityWithAccessionedSequence:R-BTA-65888] GTF2B [nucleoplasm] [Complex:R-BTA-71307] RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] [Complex:R-BTA-109629] TFIIA [nucleoplasm] [Complex:R-BTA-109626] TFIID [nucleoplasm] [Complex:R-BTA-109633] TFIIE [nucleoplasm] [Complex:R-BTA-109634] TFIIH [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-BTA-75869] Addition of the fourth nucleotide on the Nascent Transcript: Second Transition - Bos taurus [BlackBoxEvent:R-BTA-75850] Addition of the third nucleotide on the nascent transcript - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-75856
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-674695] RNA Polymerase II Pre-transcription Events
(inferredTo)	[Reaction:R-HSA-75856] Abortive Initiation Before Second Transition