Reactome | dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]

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dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] Show undefined attributes

catalystActivity	[CatalystActivity:10336620] nucleoside monophosphate kinase activity of DTYMK dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10336622
displayName	dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]
eventOf	[Pathway:R-BTA-499943] Interconversion of nucleotide di- and triphosphates - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-482619] (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) - Bos taurus
inferredFrom	[Reaction:R-HSA-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [DefinedSet:R-ALL-499997] dUMP, TMP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] phosphorylation of dUMP or TMP to dUDP or TDP dUMP + ATP => dUDP + ADP dTMP + ATP => dTDP + ADP
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [DefinedSet:R-ALL-499999] dUDP, TDP [cytosol]
precedingEvent	[Reaction:R-BTA-73596] dCMP + H2O => dUMP + NH4+ - Bos taurus [Reaction:R-BTA-73605] conversion of dUMP to dTMP - Bos taurus [Reaction:R-BTA-73632] phosphorylation of 2'-Deoxythymidine to dTMP - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-73635
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-499943] Interconversion of nucleotide di- and triphosphates
(precedingEvent)	[Reaction:R-BTA-482619] (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3)
(inferredTo)	[Reaction:R-HSA-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK]

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