Reactome | PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane

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PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane Show undefined attributes

catalystActivity	[CatalystActivity:10417346] phosphatidylinositol-3-phosphate phosphatase activity of MTMR6:MTMR9,MTMR8:MTMR9 [cytosol]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10417348
displayName	PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane
eventOf	[Pathway:R-BTA-1660499] Synthesis of PIPs at the plasma membrane - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6809325] PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-1806276] PI3P [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane
output	[SimpleEntity:R-ALL-29372] Pi [cytosol] [SimpleEntity:R-ALL-426658] PI [plasma membrane]
precedingEvent	[Reaction:R-BTA-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane - Bos taurus [Reaction:R-BTA-1675836] PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-6809325
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-1660499] Synthesis of PIPs at the plasma membrane
(inferredTo)	[Reaction:R-HSA-6809325] PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane

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