Reactome | S100A1 binds TLR4:LY96

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10416598
displayName	S100A1 binds TLR4:LY96
eventOf	[Pathway:R-BTA-5686938] Regulation of TLR by endogenous ligand - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6805943] S100A1 binds TLR4:LY96 - Homo sapiens
input	[Complex:R-BTA-6805958] S100A1 dimer:Ca(2+) [extracellular region] [Complex:R-BTA-166050] TLR4:LY96 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	S100A1 binds TLR4:LY96
output	[Complex:R-BTA-6805997] S100A1:TLR4:LY96 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-6805943
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-5686938] Regulation of TLR by endogenous ligand
(inferredTo)	[Reaction:R-HSA-6805943] S100A1 binds TLR4:LY96