Reactome | PGLYRP2 hydrolyzes bacterial peptidoglycan

Schema > BlackBoxEvent > Entries

PGLYRP2 hydrolyzes bacterial peptidoglycan Show undefined attributes

catalystActivity	[CatalystActivity:10415047] N-acetylmuramoyl-L-alanine amidase activity of PGLYRP2 dimer [extracellular region]
category	omitted
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10415049
displayName	PGLYRP2 hydrolyzes bacterial peptidoglycan
eventOf	[Pathway:R-BTA-6803157] Antimicrobial peptides - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-6799977] PGLYRP2 hydrolyzes bacterial peptidoglycan - Homo sapiens
input	[SimpleEntity:R-ALL-109276] H2O [extracellular region] [Complex:R-BTA-6799988] PGLYRP2:peptidoglycan [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	PGLYRP2 hydrolyzes bacterial peptidoglycan
output	[Polymer:R-ALL-6799970] (GlcNAc+MurNac)n [extracellular region] [SimpleEntity:R-ALL-6799975] L-Ala-gamma-D-Glu-L-Lys-D-Ala [extracellular region] [Complex:R-BTA-8933468] PGLYRP2 dimer [extracellular region]
precedingEvent	[Reaction:R-BTA-6799981] PGLYRP2 binds bacterial peptidoglycan - Bos taurus
regulatedBy	[Requirement:R-HSA-158223] Requirement by 'Zn2+ [extracellular region]'
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48898] Bos taurus
stId	R-BTA-6799977
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-6803157] Antimicrobial peptides
(inferredTo)	[BlackBoxEvent:R-HSA-6799977] PGLYRP2 hydrolyzes bacterial peptidoglycan

Cite Us!