Reactome | PPP2A-PPPR5C:CCNG1:(p-T218-MDM2, p-S166-MDM2) [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10411897] protein serine/threonine phosphatase activity of PPP2A-PPPR5C:CCNG1:(p-T218-MDM2, p-S166-MDM2) [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-BTA-6792863] PP2A-PP2R5C dephosphorylates MDM2 - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10411896
displayName	PPP2A-PPPR5C:CCNG1:(p-T218-MDM2, p-S166-MDM2) [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-BTA-6792489] CCNG1 [nucleoplasm] [EntityWithAccessionedSequence:R-BTA-6792862] phospho-MDM2 [nucleoplasm] [Complex:R-BTA-6792873] PP2A-PPP2R5C [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-6792868] PPP2A-PPPR5C:CCNG1:(p-T218-MDM2, p-S166-MDM2) [nucleoplasm] - Homo sapiens
maxDepth	4
name	PPP2A-PPPR5C:CCNG1:(p-T218-MDM2, p-S166-MDM2)
producedByEvent	[Reaction:R-BTA-6792871] CCNG1 recruits PP2A-PPP2R5C to MDM2 - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-6792868
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-BTA-6792863] PP2A-PP2R5C dephosphorylates MDM2
(physicalEntity)	[CatalystActivity:10411897] protein serine/threonine phosphatase activity of PPP2A-PPPR5C:CCNG1:(p-T218-MDM2, p-S166-MDM2) [nucleoplasm]
(output)	[Reaction:R-BTA-6792871] CCNG1 recruits PP2A-PPP2R5C to MDM2
(inferredTo)	[Complex:R-HSA-6792868] PPP2A-PPPR5C:CCNG1:(p-T218-MDM2, p-S166-MDM2) [nucleoplasm]

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