Reactome | NAALADases hydrolyse NAAG

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NAALADases hydrolyse NAAG Show undefined attributes

catalystActivity	[CatalystActivity:10408635] dipeptidase activity of NAALADases [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10408637
displayName	NAALADases hydrolyse NAAG
eventOf	[Pathway:R-BTA-8963693] Aspartate and asparagine metabolism - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-5691507] ASPA deacetylates NAASP to acetate and L-aspartate - Bos taurus [Reaction:R-BTA-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Bos taurus [Reaction:R-BTA-372448] SLC25A12,13 exchange L-Glu and L-Asp - Bos taurus
inferredFrom	[Reaction:R-HSA-5693783] NAALADases hydrolyse NAAG - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-5693762] NAAG [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	NAALADases hydrolyse NAAG H2O + N-acetyl-L-aspartyl-L-glutamate => L-glutamate + N-acetyl-L-aspartate
output	[SimpleEntity:R-ALL-29404] L-Glu [cytosol] [SimpleEntity:R-ALL-5693772] NAASP [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-5693783
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-8963693] Aspartate and asparagine metabolism
(precedingEvent)	[Reaction:R-BTA-372448] SLC25A12,13 exchange L-Glu and L-Asp [Reaction:R-BTA-5691507] ASPA deacetylates NAASP to acetate and L-aspartate [Reaction:R-BTA-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1]
(inferredTo)	[Reaction:R-HSA-5693783] NAALADases hydrolyse NAAG

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