Reactome | USP16,USP21 deubiquitinate Histone H2A

Schema > Reaction > Entries

USP16,USP21 deubiquitinate Histone H2A Show undefined attributes

catalystActivity	[CatalystActivity:10407701] cysteine-type deubiquitinase activity of USP16,USP21:Ub-histone H2A [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10407703
displayName	USP16,USP21 deubiquitinate Histone H2A
eventOf	[Pathway:R-BTA-5689880] Ub-specific processing proteases - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5690157] USP16,USP21 deubiquitinate Histone H2A - Homo sapiens
input	[SimpleEntity:R-ALL-113518] H2O [nucleoplasm] [Complex:R-BTA-6782784] USP16,USP21:Ub-histone H2A [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	USP16,USP21 deubiquitinate Histone H2A
output	[DefinedSet:R-BTA-68524] Ub [nucleoplasm] [Complex:R-BTA-6782828] USP16,USP22:Histone H2A [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-5690157
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-5689880] Ub-specific processing proteases
(inferredTo)	[Reaction:R-HSA-5690157] USP16,USP21 deubiquitinate Histone H2A

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