Reactome | TRAF3 binds BAFFR:BAFF

Schema > Reaction > Entries

TRAF3 binds BAFFR:BAFF Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10404986
displayName	TRAF3 binds BAFFR:BAFF
eventOf	[Pathway:R-BTA-5676594] TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5676596] TRAF3 binds BAFFR:BAFF - Homo sapiens
input	[Complex:R-BTA-5676540] 3xBAFFR:BAFF trimer [plasma membrane] [Complex:R-BTA-5668435] cIAP1,2:TRAF2:TRAF3:NIK [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	TRAF3 binds BAFFR:BAFF
output	[Complex:R-BTA-5676561] 3xBAFFR:BAFF trimer:TRAF3:NIK [plasma membrane]
precedingEvent	[Reaction:R-BTA-5676599] sBAFF trimer binds BAFFR - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-5676596
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-5676594] TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
(inferredTo)	[Reaction:R-HSA-5676596] TRAF3 binds BAFFR:BAFF