Reactome | CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate

Schema > Reaction > Entries

CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate Show undefined attributes

catalystActivity	[CatalystActivity:10403687] L-gulonate 3-dehydrogenase activity of CRYL1 dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10403689
displayName	CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate
eventOf	[Pathway:R-BTA-5661270] Formation of xylulose-5-phosphate - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5661290] CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate - Homo sapiens
input	[SimpleEntity:R-ALL-5661268] L-gulonate [cytosol] [SimpleEntity:R-ALL-29360] NAD+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate L-gulonate + NAD+ => 3-dehydro-L-gulonate + NADH + H+
output	[SimpleEntity:R-ALL-5661262] 3-dehydro-L-gulonate [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-73473] NADH [cytosol]
precedingEvent	[Reaction:R-BTA-5661256] AKR1A1 reduces D-glucuronate to L-gulonate - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-5661290
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-5661270] Formation of xylulose-5-phosphate
(inferredTo)	[Reaction:R-HSA-5661290] CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate

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