Reactome | SORD oxidizes D-sorbitol to Fru

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SORD oxidizes D-sorbitol to Fru Show undefined attributes

catalystActivity	[CatalystActivity:10402864] L-iditol 2-dehydrogenase (NAD+) activity of SORD tetramer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10402866
displayName	SORD oxidizes D-sorbitol to Fru
eventOf	[Pathway:R-BTA-5652227] Fructose biosynthesis - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5652195] SORD oxidizes D-sorbitol to Fru - Homo sapiens
input	[SimpleEntity:R-ALL-5652213] D-sorbitol [cytosol] [SimpleEntity:R-ALL-29360] NAD+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SORD oxidizes D-sorbitol to Fru D-sorbitol + NAD(+) => H(+) + keto-D-fructose + NADH sorbitol + NAD+ => fructose + NADH + H+
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-9832975] keto-D-Fru [cytosol] [SimpleEntity:R-ALL-73473] NADH [cytosol]
precedingEvent	[Reaction:R-BTA-5652172] AKR1B1 reduces Glc to D-sorbitol - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-5652195
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-5652227] Fructose biosynthesis
(inferredTo)	[Reaction:R-HSA-5652195] SORD oxidizes D-sorbitol to Fru

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