Reactome | NOTUM releases Hh-Np:GPC5 from the plasma membrane

Schema > Reaction > Entries

NOTUM releases Hh-Np:GPC5 from the plasma membrane Show undefined attributes

catalystActivity	[CatalystActivity:10399689] C-type glycerophospholipase activity of NOTUM [extracellular region]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10399691
displayName	NOTUM releases Hh-Np:GPC5 from the plasma membrane
eventOf	[Pathway:R-BTA-5362798] Release of Hh-Np from the secreting cell - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5362553] NOTUM releases Hh-Np:GPC5 from the plasma membrane - Homo sapiens
input	[Complex:R-BTA-5362428] Hh-Np:GPI-GPC5 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	NOTUM releases Hh-Np:GPC5 from the plasma membrane
output	[Complex:R-BTA-5362546] Hh-Np:GPC5 [extracellular region]
precedingEvent	[Reaction:R-BTA-5362427] Hh-Np binds GPC5 - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-5362553
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-5362798] Release of Hh-Np from the secreting cell
(inferredTo)	[Reaction:R-HSA-5362553] NOTUM releases Hh-Np:GPC5 from the plasma membrane

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