Reactome | Pellino ubiquitinates IRAK1

Schema > Reaction > Entries

catalystActivity	[CatalystActivity:10366870] ubiquitin-protein transferase activity of hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10366872
displayName	Pellino ubiquitinates IRAK1
eventOf	[Pathway:R-BTA-9020702] Interleukin-1 signaling - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-451418] Pellino ubiquitinates IRAK1 - Homo sapiens
input	[Complex:R-BTA-8948064] hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Pellino ubiquitinates IRAK1
output	[Complex:R-BTA-8948058] K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-451418
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-9020702] Interleukin-1 signaling
(inferredTo)	[Reaction:R-HSA-451418] Pellino ubiquitinates IRAK1

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