Reactome | IL7:IL7R:JAK1 binds IL2RG:JAK3

Schema > Reaction > Entries

IL7:IL7R:JAK1 binds IL2RG:JAK3 Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10366319
displayName	IL7:IL7R:JAK1 binds IL2RG:JAK3
eventOf	[Pathway:R-BTA-1266695] Interleukin-7 signaling - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-BTA-8983063] JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated - Bos taurus
inferredFrom	[Reaction:R-HSA-449958] IL7:IL7R:JAK1 binds IL2RG:JAK3 - Homo sapiens
input	[Complex:R-BTA-451911] IL2RG:JAK3 [plasma membrane] [Complex:R-BTA-449983] IL7:IL7R:JAK1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	IL7:IL7R:JAK1 binds IL2RG:JAK3
output	[Complex:R-BTA-449967] IL7:IL7R:JAK1:IL2RG:JAK3 [plasma membrane]
precedingEvent	[Reaction:R-BTA-451895] IL2RG binds JAK3 - Bos taurus [Reaction:R-BTA-449978] IL7 binds IL7R:JAK1 - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-449958
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-1266695] Interleukin-7 signaling
(precedingEvent)	[BlackBoxEvent:R-BTA-8983063] JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated
(inferredTo)	[Reaction:R-HSA-449958] IL7:IL7R:JAK1 binds IL2RG:JAK3

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