Reactome | T1R2/T1R3 dimer is a sweet taste receptor

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T1R2/T1R3 dimer is a sweet taste receptor Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10365181
displayName	T1R2/T1R3 dimer is a sweet taste receptor
eventOf	[Pathway:R-BTA-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi - Bos taurus
inferredFrom	[Reaction:R-HSA-444606] T1R2/T1R3 dimer is a sweet taste receptor - Homo sapiens
input	[DefinedSet:R-ALL-444679] Sweet taste compounds [extracellular region] [Complex:R-BTA-444621] TAS1R2:TAS1R3 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	T1R2/T1R3 dimer is a sweet taste receptor
output	[Complex:R-BTA-444662] TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-444606
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-420499] Class C/3 (Metabotropic glutamate/pheromone receptors)
(precedingEvent)	[Reaction:R-BTA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi
(inferredTo)	[Reaction:R-HSA-444606] T1R2/T1R3 dimer is a sweet taste receptor

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