Reactome | MBD2 binds methylcytosine in chromatin

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10363364
displayName	MBD2 binds methylcytosine in chromatin
eventOf	[Pathway:R-BTA-427413] NoRC negatively regulates rRNA expression - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-427337] MBD2 binds methylcytosine in chromatin - Homo sapiens
input	[Complex:R-BTA-5226877] Chromatin with H3K9me2, 5mC [nucleoplasm] [EntityWithAccessionedSequence:R-BTA-427367] MBD2 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	MBD2 binds methylcytosine in chromatin
output	[Complex:R-BTA-427343] Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-427337
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-427413] NoRC negatively regulates rRNA expression
(inferredTo)	[Reaction:R-HSA-427337] MBD2 binds methylcytosine in chromatin

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