Reactome | CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac

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CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac Show undefined attributes

catalystActivity	[CatalystActivity:10395504] N-acylneuraminate cytidylyltransferase activity of CMAS tetramer [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10395506
displayName	CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac
eventOf	[Pathway:R-BTA-4085001] Sialic acid metabolism - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-4084982] CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac - Homo sapiens
input	[SimpleEntity:R-ALL-29470] CTP [nucleoplasm] [SimpleEntity:R-ALL-4085414] Neu5Ac [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac N-acetylneuraminate + CTP => CMP-N-acetyl-beta-neuraminate + diphosphate
output	[SimpleEntity:R-ALL-4085418] CMP-Neu5Ac [nucleoplasm] [SimpleEntity:R-ALL-113541] PPi [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-4084982
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-4085001] Sialic acid metabolism
(inferredTo)	[Reaction:R-HSA-4084982] CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac

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