Reactome | Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10360551
displayName	Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-BTA-167542] CD4 [plasma membrane] [Complex:R-BTA-203463] MHC Class II bearing antigen peptide [plasma membrane] [EntityWithAccessionedSequence:R-BTA-202308] phospho-LCK [cytosol] [Complex:R-BTA-390341] T-cell receptor complex with dephosphorylated CD3 zeta chain [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-390339] Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane] - Homo sapiens
maxDepth	6
name	Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4
producedByEvent	[Reaction:R-BTA-389758] Dephosphorylation of CD3-zeta by PD-1 bound phosphatases - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-390339
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-BTA-389758] Dephosphorylation of CD3-zeta by PD-1 bound phosphatases
(inferredTo)	[Complex:R-HSA-390339] Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane]

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