Reactome | RAP1A exchanges GDP for GTP

Schema > Reaction > Entries

RAP1A exchanges GDP for GTP Show undefined attributes

catalystActivity	[CatalystActivity:10359652] guanyl-nucleotide exchange factor activity of Epac1,2:cAMP complex [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10359654
displayName	RAP1A exchanges GDP for GTP
eventOf	[Pathway:R-BTA-381676] Glucagon-like Peptide-1 (GLP1) regulates insulin secretion - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-381727] RAP1A exchanges GDP for GTP - Homo sapiens
input	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-BTA-5252143] RAP1A:GDP [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	RAP1A exchanges GDP for GTP
output	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-BTA-5252145] RAP1A:GTP [plasma membrane]
precedingEvent	[Reaction:R-BTA-381668] cAMP activates EPAC1 - Bos taurus [Reaction:R-BTA-381608] cAMP activates EPAC2 - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-381727
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-381676] Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
(inferredTo)	[Reaction:R-HSA-381727] RAP1A exchanges GDP for GTP