Reactome | DCC interaction with Ezrin

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10356849
displayName	DCC interaction with Ezrin
eventOf	[Pathway:R-BTA-373752] Netrin-1 signaling - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-374663] DCC interaction with Ezrin - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-197560] DCC [plasma membrane] [Complex:R-BTA-374558] p-T567-EZR:PIP2 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	DCC interaction with Ezrin
output	[Complex:R-BTA-374565] DCC:p-T567-EZR:PIP2 [plasma membrane]
precedingEvent	[Reaction:R-BTA-374664] Phosphorylation and activation of Ezrin - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-374663
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-373752] Netrin-1 signaling
(inferredTo)	[Reaction:R-HSA-374663] DCC interaction with Ezrin

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