Reactome | Phosphorylation of BCAR1 by SRC-PTK2 complex

Schema > Reaction > Entries

Phosphorylation of BCAR1 by SRC-PTK2 complex Show undefined attributes

catalystActivity	[CatalystActivity:10356280] protein tyrosine kinase activity of BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10356282
displayName	Phosphorylation of BCAR1 by SRC-PTK2 complex
eventOf	[Pathway:R-BTA-372708] p130Cas linkage to MAPK signaling for integrins - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-372697] Crk binding to p130cas - Bos taurus
inferredFrom	[Reaction:R-HSA-372693] Phosphorylation of BCAR1 by SRC-PTK2 complex - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-BTA-372688] BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylation of BCAR1 by SRC-PTK2 complex
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-BTA-372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane]
precedingEvent	[Reaction:R-BTA-372705] Recruitment of BCAR1 to PTK2 complex - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-372693
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-372708] p130Cas linkage to MAPK signaling for integrins
(precedingEvent)	[Reaction:R-BTA-372697] Crk binding to p130cas
(inferredTo)	[Reaction:R-HSA-372693] Phosphorylation of BCAR1 by SRC-PTK2 complex

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