Reactome | Attenuation phase

Schema > Pathway > Entries

created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10445372
displayName	Attenuation phase
eventOf	[Pathway:R-BTA-3371571] HSF1-dependent transactivation - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-BTA-5082384] HSP70:DNAJB1 binds HSF1 - Bos taurus [Reaction:R-BTA-3371554] HSF1 acetylation at Lys80 - Bos taurus [Reaction:R-BTA-3371582] HSBP1 binds HSF1 trimer - Bos taurus [Reaction:R-BTA-5324617] HSP90:FKBP4:PTGES3 binds HSF1 trimer - Bos taurus
inferredFrom	[Pathway:R-HSA-3371568] Attenuation phase - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Attenuation phase
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-3371568
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-3371571] HSF1-dependent transactivation
(inferredTo)	[Pathway:R-HSA-3371568] Attenuation phase