Reactome | RANBP2 SUMOylates PML with SUMO2

Schema > Reaction > Entries

RANBP2 SUMOylates PML with SUMO2 Show undefined attributes

catalystActivity	[CatalystActivity:10391315] SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope]
category	transition
compartment	[Compartment:7660] nucleoplasm [Compartment:13231] nuclear envelope
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10391317
displayName	RANBP2 SUMOylates PML with SUMO2
eventOf	[Pathway:R-BTA-3108214] SUMOylation of DNA damage response and repair proteins - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-3000411] RANBP2 SUMOylates PML with SUMO2 - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-1031706] PML [nucleoplasm] 6 × [Complex:R-BTA-2993778] SUMO2:UBE2I [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	RANBP2 SUMOylates PML with SUMO2 Conjugation of SUMO2 to PML
output	[EntityWithAccessionedSequence:R-BTA-3000423] PML [nucleoplasm] 6 × [EntityWithAccessionedSequence:R-BTA-912481] UBE2I [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-3000411
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-3108214] SUMOylation of DNA damage response and repair proteins
(inferredTo)	[Reaction:R-HSA-3000411] RANBP2 SUMOylates PML with SUMO2

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