Reactome | LPL hydrolyses TGs from mature CMs

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LPL hydrolyses TGs from mature CMs Show undefined attributes

catalystActivity	[CatalystActivity:10346921] lipoprotein lipase activity of GPIHBP1:HSPG:LPL dimer [plasma membrane]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10388716
displayName	LPL hydrolyses TGs from mature CMs
eventOf	[Pathway:R-BTA-975634] Retinoid metabolism and transport - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-2423785] CR:atREs binds apoE and HSPG - Bos taurus
inferredFrom	[Reaction:R-HSA-2395768] LPL hydrolyses TGs from mature CMs - Homo sapiens
input	[Complex:R-BTA-2395771] mature CM:atREs [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	LPL hydrolyses TGs from mature CMs Lipoprotein lipase (LPL) hydrolyses triacylglycerols (TGs) from mature chylomicrons (CM)
output	[Complex:R-BTA-2569093] CR:atREs [extracellular region] 50 × [SimpleEntity:R-ALL-174675] DAGs [extracellular region] 50 × [SimpleEntity:R-ALL-174602] LCFAs [extracellular region]
precedingEvent	[BlackBoxEvent:R-BTA-2395784] Nascent CMs transform into mature CMs - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-2395768
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-975634] Retinoid metabolism and transport
(precedingEvent)	[Reaction:R-BTA-2423785] CR:atREs binds apoE and HSPG
(inferredTo)	[Reaction:R-HSA-2395768] LPL hydrolyses TGs from mature CMs

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