Reactome | p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]

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p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-BTA-205177] PI3K:p-KIT:sSCF dimer:p-KIT [plasma membrane] - Bos taurus [Complex:R-BTA-205201] Tyrosine kinases:p-KIT complex [plasma membrane] - Bos taurus
consumedByEvent	[Reaction:R-BTA-1433501] Interaction of other adapter proteins with p-KIT - Bos taurus [Reaction:R-BTA-205262] Direct recruitment of PI3K to p-KIT - Bos taurus [Reaction:R-BTA-205328] Interaction of other tyrosine kinases with p-KIT - Bos taurus [Reaction:R-BTA-205306] Interaction of SHP1 and KIT - Bos taurus [Reaction:R-BTA-1562640] LNK binds to p-KIT and inhibit downstream signaling - Bos taurus [Reaction:R-BTA-205286] GRB2:SOS interacts with p-KIT - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10353828
displayName	p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]
hasComponent	2 × [EntityWithAccessionedSequence:R-BTA-205207] phospho-p-7Y-KIT [plasma membrane] [Complex:R-BTA-1433307] sSCF dimer [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-205310] p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane] - Homo sapiens
maxDepth	3
name	p-7Y-KIT:sSCF dimer:p-7Y-KIT
positivelyRegulates	[PositiveRegulation:10437779] Positive regulation by 'p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]'
producedByEvent	[Reaction:R-BTA-205289] Autophosphorylation of KIT - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-205310
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(regulator)	[PositiveRegulation:10437779] Positive regulation by 'p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]'
(input)	[Reaction:R-BTA-205328] Interaction of other tyrosine kinases with p-KIT [Reaction:R-BTA-1433501] Interaction of other adapter proteins with p-KIT [Reaction:R-BTA-205306] Interaction of SHP1 and KIT [Reaction:R-BTA-1562640] LNK binds to p-KIT and inhibit downstream signaling [Reaction:R-BTA-205286] GRB2:SOS interacts with p-KIT [Reaction:R-BTA-205262] Direct recruitment of PI3K to p-KIT
(hasComponent)	[Complex:R-BTA-205201] Tyrosine kinases:p-KIT complex [plasma membrane] [Complex:R-BTA-1433538] Adapter proteins:p-KIT complex [plasma membrane] [Complex:R-BTA-205181] PTPN6:p-c-Kit complex [plasma membrane] [Complex:R-BTA-1562562] LNK:p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane] [Complex:R-BTA-205271] SFKs:p-KIT complex [plasma membrane] [Complex:R-BTA-205202] GRB2:SOS1:p-KIT complex [plasma membrane] [Complex:R-BTA-205177] PI3K:p-KIT:sSCF dimer:p-KIT [plasma membrane]
(output)	[Reaction:R-BTA-205289] Autophosphorylation of KIT
(inferredTo)	[Complex:R-HSA-205310] p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]

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