Reactome | Interaction of Csk with PAG

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10353062
displayName	Interaction of Csk with PAG
eventOf	[Pathway:R-BTA-202427] Phosphorylation of CD3 and TCR zeta chains - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-202233] Inactivation of Lck by Csk - Bos taurus
inferredFrom	[Reaction:R-HSA-203774] Interaction of Csk with PAG - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-203776] CSK [cytosol] [EntityWithAccessionedSequence:R-BTA-180494] phospho-PAG1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Interaction of Csk with PAG
output	[Complex:R-BTA-202297] Csk:p-PAG [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-203774
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-202427] Phosphorylation of CD3 and TCR zeta chains
(precedingEvent)	[Reaction:R-BTA-202233] Inactivation of Lck by Csk
(inferredTo)	[Reaction:R-HSA-203774] Interaction of Csk with PAG

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