Reactome | WWTR1 (TAZ) binds TEAD

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10385388
displayName	WWTR1 (TAZ) binds TEAD
eventOf	[Pathway:R-BTA-2032785] YAP1- and WWTR1 (TAZ)-stimulated gene expression - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2032781] WWTR1 (TAZ) binds TEAD - Homo sapiens
input	[DefinedSet:R-BTA-2032773] TEADs [nucleoplasm] [EntityWithAccessionedSequence:R-BTA-1629775] WWTR1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	WWTR1 (TAZ) binds TEAD
output	[Complex:R-BTA-2032762] TEAD:WWTR1(TAZ) [nucleoplasm]
precedingEvent	[Reaction:R-BTA-2032768] Translocation of WWTR1 (TAZ) to the nucleus - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-2032781
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-2032785] YAP1- and WWTR1 (TAZ)-stimulated gene expression
(inferredTo)	[Reaction:R-HSA-2032781] WWTR1 (TAZ) binds TEAD

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