Reactome | Dynein:Dynactin:microtubule [cytosol]

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-BTA-8849246] Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] - Bos taurus [Complex:R-BTA-8849336] RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] - Bos taurus
consumedByEvent	[Reaction:R-BTA-6809003] ERGIC-to-Golgi vesicles bind dynein:dynactin - Bos taurus [BlackBoxEvent:R-BTA-2213248] Transport of antigen loaded MHC II molecules to surface - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10388150
displayName	Dynein:Dynactin:microtubule [cytosol]
hasComponent	[Complex:R-BTA-2029120] Dynactin [cytosol] [Complex:R-BTA-2029145] Dynein complex [cytosol] [Complex:R-BTA-190599] Microtubule [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-2029135] Dynein:Dynactin:microtubule [cytosol] - Homo sapiens
maxDepth	8
name	Dynein:Dynactin:microtubule
positivelyRegulates	[PositiveRegulation:10401228] Positive regulation by 'Dynein:Dynactin:microtubule [cytosol]'
producedByEvent	[BlackBoxEvent:R-BTA-2213248] Transport of antigen loaded MHC II molecules to surface - Bos taurus [BlackBoxEvent:R-BTA-8849353] Dynein drives COPI-independent retrograde traffic from the Golgi to the ER - Bos taurus [Reaction:R-BTA-6809006] Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-2029135
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[BlackBoxEvent:R-BTA-8849353] Dynein drives COPI-independent retrograde traffic from the Golgi to the ER [BlackBoxEvent:R-BTA-2213248] Transport of antigen loaded MHC II molecules to surface [Reaction:R-BTA-6809006] Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex
(hasComponent)	[Complex:R-BTA-8849336] RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] [Complex:R-BTA-8849246] Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] [Complex:R-BTA-6808904] RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle]
(input)	[BlackBoxEvent:R-BTA-2213248] Transport of antigen loaded MHC II molecules to surface [Reaction:R-BTA-6809003] ERGIC-to-Golgi vesicles bind dynein:dynactin
(regulator)	[PositiveRegulation:10401228] Positive regulation by 'Dynein:Dynactin:microtubule [cytosol]'
(inferredTo)	[Complex:R-HSA-2029135] Dynein:Dynactin:microtubule [cytosol]

Dynein:Dynactin:microtubule [cytosol] Show undefined attributes

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