Reactome | Cytosolic folate export across the plasma membrane

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Cytosolic folate export across the plasma membrane Show undefined attributes

catalystActivity	[CatalystActivity:10351548] folic acid:proton symporter activity of SLC46A1 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10351550
displayName	Cytosolic folate export across the plasma membrane
eventOf	[Pathway:R-BTA-196757] Metabolism of folate and pterines - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-200646] Cytosolic folate export across the plasma membrane - Homo sapiens
input	[SimpleEntity:R-ALL-197965] FOLA [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Cytosolic folate export across the plasma membrane SLC46A1 transports FOLA from cytosol to extracellular region
output	[SimpleEntity:R-ALL-200716] FOLA [extracellular region] [SimpleEntity:R-ALL-351626] H+ [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-200646
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-196757] Metabolism of folate and pterines
(inferredTo)	[Reaction:R-HSA-200646] Cytosolic folate export across the plasma membrane

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