Reactome | CSGALNACTs transfer GalNAc to CS linker glycan

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CSGALNACTs transfer GalNAc to CS linker glycan Show undefined attributes

catalystActivity	[CatalystActivity:10382403] glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity of CSGALNACT [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10382405
displayName	CSGALNACTs transfer GalNAc to CS linker glycan
eventOf	[Pathway:R-BTA-2022870] CS-GAG biosynthesis - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-1971491] Chondroitin polymerase complex transfers GlcA to CS chain - Bos taurus
inferredFrom	[Reaction:R-HSA-1971482] CSGALNACTs transfer GalNAc to CS linker glycan - Homo sapiens
input	[DefinedSet:R-BTA-2064233] GlcA-Gal-Gal-Xyl-CS proteins [Golgi lumen] [SimpleEntity:R-ALL-735700] UDP-GalNAc [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	CSGALNACTs transfer GalNAc to CS linker glycan The addition of GalNAc to the terminal glucuronate residue forms chondroitin
output	[DefinedSet:R-BTA-2064172] chondroitin(1)-core proteins [Golgi lumen] [SimpleEntity:R-ALL-425969] H+ [Golgi lumen] [SimpleEntity:R-ALL-205687] UDP [Golgi lumen]
precedingEvent	[Reaction:R-BTA-1889955] B3GAT dimers transfer GlcA to tetrasaccharide linker - Bos taurus [Reaction:R-BTA-735702] SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-1971482
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-2022870] CS-GAG biosynthesis
(precedingEvent)	[Reaction:R-BTA-1971491] Chondroitin polymerase complex transfers GlcA to CS chain
(inferredTo)	[Reaction:R-HSA-1971482] CSGALNACTs transfer GalNAc to CS linker glycan

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