Reactome | RPA binds to the Flap on the C-strand

Schema > Reaction > Entries

RPA binds to the Flap on the C-strand Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10346769
displayName	RPA binds to the Flap on the C-strand
eventOf	[Pathway:R-BTA-174437] Removal of the Flap Intermediate from the C-strand - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-174451] Recruitment of DNA2 endonuclease to the C strand - Bos taurus
goBiologicalProcess	[GO_BiologicalProcess:263978] telomere maintenance via semi-conservative replication
inferredFrom	[Reaction:R-HSA-174445] RPA binds to the Flap on the C-strand - Homo sapiens
input	[Complex:R-BTA-174431] Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] [Complex:R-BTA-68462] RPA heterotrimer [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	RPA binds to the Flap on the C-strand
output	[Complex:R-BTA-174436] Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm]
precedingEvent	[Reaction:R-BTA-174438] Formation of the Flap Intermediate on the C-strand - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-174445
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-174437] Removal of the Flap Intermediate from the C-strand
(precedingEvent)	[Reaction:R-BTA-174451] Recruitment of DNA2 endonuclease to the C strand
(inferredTo)	[Reaction:R-HSA-174445] RPA binds to the Flap on the C-strand

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