Reactome | NGF processing

Schema > Pathway > Entries

created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10443894
displayName	NGF processing
eventOf	[Pathway:R-BTA-9036866] Expression and Processing of Neurotrophins - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-BTA-187015] Activation of TRKA receptors - Bos taurus
goBiologicalProcess	[GO_BiologicalProcess:190080] nerve growth factor processing
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-BTA-187020] Part of pro-beta-NGF is processed to mature beta-NGF - Bos taurus [Reaction:R-BTA-187035] Pro-beta-NGF and mature beta-NGF are secreted - Bos taurus
inferredFrom	[Pathway:R-HSA-167060] NGF processing - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	NGF processing
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-167060
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-9036866] Expression and Processing of Neurotrophins
(precedingEvent)	[Pathway:R-BTA-187015] Activation of TRKA receptors
(inferredTo)	[Pathway:R-HSA-167060] NGF processing
(hasEncapsulatedEvent)	[Pathway:R-BTA-187037] Signaling by NTRK1 (TRKA) [Pathway:R-BTA-193704] p75 NTR receptor-mediated signalling

Cite Us!