Reactome | Transfer of LPS from LBP carrier to CD14

Schema > Pathway > Entries

compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10443618
displayName	Transfer of LPS from LBP carrier to CD14
eventOf	[Pathway:R-BTA-166016] Toll Like Receptor 4 (TLR4) Cascade - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-BTA-166038] GPI-bound CD14 binds LPS - Bos taurus [Reaction:R-BTA-169719] Secreted CD14 binds LPS - Bos taurus
inferredFrom	[Pathway:R-HSA-166020] Transfer of LPS from LBP carrier to CD14 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Transfer of LPS from LBP carrier to CD14
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-166020
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-166016] Toll Like Receptor 4 (TLR4) Cascade
(inferredTo)	[Pathway:R-HSA-166020] Transfer of LPS from LBP carrier to CD14

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