Reactome | SPRY2 is serine phosphorylated in response to MAPK activation

Schema > BlackBoxEvent > Entries

SPRY2 is serine phosphorylated in response to MAPK activation Show undefined attributes

category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10376182
displayName	SPRY2 is serine phosphorylated in response to MAPK activation
eventOf	[Pathway:R-BTA-1295596] Spry regulation of FGF signaling - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-1295604] B-RAF dissociates from S110/S120 p-SPRY2 - Bos taurus
inferredFrom	[BlackBoxEvent:R-HSA-1295634] SPRY2 is serine phosphorylated in response to MAPK activation - Homo sapiens
input	[Complex:R-BTA-1295598] SPRY2:B-RAF [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SPRY2 is serine phosphorylated in response to MAPK activation
output	[Complex:R-BTA-1295587] S110/S120 p-SPRY2:B-RAF [cytosol]
regulatedBy	[Requirement:10376183] Requirement by 'p-T,Y MAPK dimers [cytosol]'
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48898] Bos taurus
stId	R-BTA-1295634
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-1295596] Spry regulation of FGF signaling
(precedingEvent)	[Reaction:R-BTA-1295604] B-RAF dissociates from S110/S120 p-SPRY2
(inferredTo)	[BlackBoxEvent:R-HSA-1295634] SPRY2 is serine phosphorylated in response to MAPK activation

Cite Us!