Reactome | p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP

Schema > Reaction > Entries

p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP Show undefined attributes

catalystActivity	[CatalystActivity:10374838] guanyl-nucleotide exchange factor activity of p-RASGRP1,3:DAG [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10374840
displayName	p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP
eventOf	[Pathway:R-BTA-1169092] Activation of RAS in B cells - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1168636] p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP - Homo sapiens
input	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-BTA-109796] p21 RAS:GDP [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP Activation of RAS by RasGRP1 and RasGRP3
output	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-BTA-109783] p21 RAS:GTP [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-1168636
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-1169092] Activation of RAS in B cells
(inferredTo)	[Reaction:R-HSA-1168636] p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP

Cite Us!