Reactome | Translocation of phosphorylated IRF3,IRF7 dimers into nucleus

Schema > Reaction > Entries

Translocation of phosphorylated IRF3,IRF7 dimers into nucleus Show undefined attributes

category	transition
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10374630
displayName	Translocation of phosphorylated IRF3,IRF7 dimers into nucleus
eventOf	[Pathway:R-BTA-918233] TRAF3-dependent IRF activation pathway - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-1028820] Formation of VAF (virus-activated factor) complex - Bos taurus
inferredFrom	[Reaction:R-HSA-1028816] Translocation of phosphorylated IRF3,IRF7 dimers into nucleus - Homo sapiens
input	[Complex:R-BTA-1027367] IRF3-P:IRF7-P [cytosol] [Complex:R-BTA-450344] p-2S-IRF7:p-2S-IRF7 [cytosol] [Complex:R-BTA-166272] p-T,4S-IRF3:p-T,4S-IRF3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Translocation of phosphorylated IRF3,IRF7 dimers into nucleus
output	[Complex:R-BTA-450306] 2xp-S477,S479-IRF7 [nucleoplasm] [Complex:R-BTA-1027365] IRF3-P:IRF7-P [nucleoplasm] [Complex:R-BTA-177675] p-T,4S-IRF3:p-T,4S-IRF3 [nucleoplasm]
precedingEvent	[Reaction:R-BTA-1028821] Dimerization of Phospho IRF3 or phospho IRF7 - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-1028816
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-BTA-1028820] Formation of VAF (virus-activated factor) complex
(hasEvent)	[Pathway:R-BTA-918233] TRAF3-dependent IRF activation pathway
(inferredTo)	[Reaction:R-HSA-1028816] Translocation of phosphorylated IRF3,IRF7 dimers into nucleus

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