Reactome | streptozocin [nucleoplasm]

Schema > ChemicalDrug > Entries

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[BlackBoxEvent:R-RNO-9732711] Streptozocin produces DNA damage in the form of O6-methylguanine in rat dsDNA - Rattus norvegicus [BlackBoxEvent:R-RNO-9730905] Streptozocin (streptozotocin) produces 7-methylguanine in dsDNA - Rattus norvegicus [BlackBoxEvent:R-RNO-9730898] Streptozocin (streptozotocin) produces 3-methyladenine in dsDNA - Rattus norvegicus
created	[InstanceEdit:9729897] Orlic-Milacic, Marija, 2021-05-04
crossReference	[DatabaseIdentifier:12021335] Mondo:0005815
dbId	9729906
disease	[Disease:1500689] cancer [Disease:9659319] islet cell tumor
displayName	streptozocin [nucleoplasm]
inDisease	true
maxDepth	1
memberOf	[DefinedSet:R-ALL-9729903] dacarbazine,procarbazine,streptozocin,temozolomide [nucleoplasm]
modified	[InstanceEdit:9749814] Orlic-Milacic, Marija, 2021-08-05
name	streptozocin streptozotocin
referenceEntity	[ReferenceTherapeutic:pubchem.compound:29327] streptozocin [PubChem Compound:29327]
schemaClass	ChemicalDrug
stId	R-ALL-9729906

(input)	[BlackBoxEvent:R-RNO-9732711] Streptozocin produces DNA damage in the form of O6-methylguanine in rat dsDNA [BlackBoxEvent:R-RNO-9730905] Streptozocin (streptozotocin) produces 7-methylguanine in dsDNA [BlackBoxEvent:R-RNO-9730898] Streptozocin (streptozotocin) produces 3-methyladenine in dsDNA
(hasMember)	[DefinedSet:R-ALL-9729903] dacarbazine,procarbazine,streptozocin,temozolomide [nucleoplasm] [CandidateSet:R-ALL-9730920] dacarbazine,streptozocin,temozolomide,(procarbazine) [nucleoplasm]