Reactome | bimatoprost acid [extracellular region]

Schema > ChemicalDrug > Entries

compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9718066] Jassal, Bijay, 2021-03-16
crossReference	[DatabaseIdentifier:12021170] Mondo:0003037 [DatabaseIdentifier:9718115] ChEBI:51230
dbId	9718078
disease	[Disease:5605152] glaucoma [Disease:9611008] ocular hypertension [Disease:9718126] hypotrichosis
displayName	bimatoprost acid [extracellular region]
inDisease	true
literatureReference	[LiteratureReference:9718039] Pharmacological characterization of a novel antiglaucoma agent, Bimatoprost (AGN 192024) [LiteratureReference:9718093] Agonist activity of bimatoprost, travoprost, latanoprost, unoprostone isopropyl ester and other prostaglandin analogs at the cloned human ciliary body FP prostaglandin receptor [LiteratureReference:9718119] Replacement of the carboxylic acid group of prostaglandin f(2alpha) with a hydroxyl or methoxy substituent provides biologically unique compounds [LiteratureReference:9718120] Bimatoprost and its free acid are prostaglandin FP receptor agonists
maxDepth	1
memberOf	[DefinedSet:R-ALL-9718005] PTGFR agonists [extracellular region]
modified	[InstanceEdit:9718121] Jassal, Bijay, 2021-03-16
name	bimatoprost acid AGN 192024 LS-181817 Lumigan®
referenceEntity	[ReferenceTherapeutic:iuphar.ligand:1959] bimatoprost (free acid form) [Guide to Pharmacology:1959]
schemaClass	ChemicalDrug
stId	R-ALL-9718078

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