Reactome | ASP-3026 [cytosol]

Schema > ChemicalDrug > Entries

compartment	[Compartment:70101] cytosol
consumedByEvent	[FailedReaction:R-HSA-9700646] ASP-3026- resistant ALK mutants don't bind ASP-3026 - Homo sapiens
created	[InstanceEdit:9702332] Rothfels, Karen, 2020-09-29
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992 [DatabaseIdentifier:9717743] ChEBI:167650
dbId	9702330
disease	[Disease:1500689] cancer
displayName	ASP-3026 [cytosol]
inDisease	true
literatureReference	[LiteratureReference:9702302] The ALK inhibitor ASP3026 eradicates NPM-ALK? T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model
maxDepth	1
memberOf	[DefinedSet:R-ALL-9699973] type I ALK-binding TKIs [cytosol]
modified	[InstanceEdit:9717734] Stephan, Ralf, 2021-03-15
name	ASP-3026 ASP3026 ASP 3026
referenceEntity	[ReferenceTherapeutic:iuphar.ligand:7740] ASP-3026 [Guide to Pharmacology:7740]
schemaClass	ChemicalDrug
stId	R-ALL-9702330

(input)	[FailedReaction:R-HSA-9700646] ASP-3026- resistant ALK mutants don't bind ASP-3026
(hasMember)	[DefinedSet:R-ALL-9699973] type I ALK-binding TKIs [cytosol]

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