Reactome | Brivanib [cytosol]

Schema > ChemicalDrug > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2023383] Rothfels, K, 2011-12-07
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992 [DatabaseIdentifier:9628050] PubChem Compound:11234052 [DatabaseIdentifier:9717716] ChEBI:94562
dbId	2023385
disease	[Disease:1500689] cancer
displayName	Brivanib [cytosol]
inDisease	true
literatureReference	[LiteratureReference:2077392] Brivanib alaninate, a dual inhibitor of vascular endothelial growth factor receptor and fibroblast growth factor receptor tyrosine kinases, induces growth inhibition in mouse models of human hepatocellular carcinoma
maxDepth	1
memberOf	[DefinedSet:R-ALL-2023441] Tyrosine kinase inhibitors of overexpressed FGFR1 [cytosol]
modified	[InstanceEdit:9717734] Stephan, Ralf, 2021-03-15
name	Brivanib BMS 540215
referenceEntity	[ReferenceTherapeutic:iuphar.ligand:5671] brivanib [Guide to Pharmacology:5671]
schemaClass	ChemicalDrug
stId	R-ALL-2023385
summation	[Summation:2077393] Brivanib, from Bristol Myers Squibb, is an FGFR and VEGFR in...

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