heme A synthase activity

accession 0120547
created [InstanceEdit:9938273] D'Eustachio, Peter, 2025-02-13
databaseName GO
dbId 9938272
definition Catalysis of the reaction: Fe(II)-heme o + 2 acceptor + H2O = Fe(II)-heme a + 2 acceptor-H2. The conversion of heme o to heme a occcurs by two successive hydroxylations of the methyl group at C8 using water as the oxygen source. The first hydroxylation forms heme i, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
displayName heme A synthase activity
ecNumber 1.17.99.9
modified [InstanceEdit:9938274] D'Eustachio, Peter, 2025-02-13
name heme A synthase activity
referenceDatabase [ReferenceDatabase:1] GO
schemaClass GO_MolecularFunction
url https://www.ebi.ac.uk/QuickGO/term/GO:0120547
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